7 Best Medical Grade Air Purifier in 2023

Recently updated on May 4th, 2023 at 12:13 pm

Medical-grade air purifiers can filter out at least 99.97% of airborne contaminants, allergens, and respiratory irritants and even neutralize odors. They offer hospital-grade protection that makes them perfect for people with severe allergies or medical conditions.

But with so many different types of air purifiers out there, it can be not easy to choose one single product. 

With a team of five members, we’ve researched for you and tested 15 air purifiers, each for at least 4 weeks, to prepare a shortlist of the best hospital-grade air purifiers.

Each manufacturer adds its technology to the H13 HEPA filter to offer complete protection. According to studies and manufacturing guidelines, the H13 HEPA filter can easily filter 99.95% of airborne contaminants, making it an ideal choice for hospital-grade protection. Let’s take a look at what each purifier brings to the table.

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Update: We have updated our review based on 6 month use so you can find more insight on how each one performs on the long run.

Best Medical Grade Air Purifier List (Comparison table)

This table will equip you with all the necessary information you need to make the ultimate decision. Read on to get a better insight on our first hand-on experience and more complete in-depth analysis of each purifier.

CADR: 300 cfm
Filteration Stages: 4
Area Coverage: 1125 sq. ft.
Budget pick
Medify MA-40
CADR: 224 cfm
Filteration Stages: 3
Area Coverage: 840 sq. ft.
Okaysou Air Purifier
CADR: 210 cfm
Filteration Stages: 5
Area Coverage: 320 sq. ft.
CADR: 71 cfm
Filteration Stages: 3
Area Coverage: 200 sq. ft.
LEVOIT Air Purifier
CADR: 130 cfm
Filteration Stages: 3
Area Coverage: 300 sq. ft.
Alen BreatheSmart 75i
CADR: 347 cfm
Filteration Stages: 4
Area Coverage: 1300 sq. ft.
CADR: 265 cfm
Filteration Stages: 5
Area Coverage: 1500 sq. ft.

1. IQAir HealthPro Plus Air Purifier

IQAir HealthPro Plus Air Purifier APM

If you’re looking for the best medical grade H13 HEPA air purifier, IQAir HealthPro Plus is for you. Thanks to its V5 cell filter, we were able to get rid of the smell of our freshly painted clinic in just within half an hour.

Through customer satisfaction and quality manufacturing, IQAir gains trust among other brands in the market. Along with the optimal air cleaning credited to the proprietary Even Flow Diffuser technology, the premium Swiss touch and design gives the air purifier a 4.8 rating.

The EvenFlow Diffuser technology ensures 320-degree clean air delivery to breathe.

We found it perfect for the hospital settings considering how it effectively removed the unpleasant odors of the medicines prevailing in the hospital environment.

Now that the unit is extremely bulky and large, the size of a mid-sized table, it was hard to move it around and find a perfect place for it. We lastly decided to place it where the patient crowd is the most.

On comparison with its precursor, we found IQAir HealthPro Plus better, considering how the air purifier has evolved. 

We found the plus version more effective in cleaning odors, gaseous pollutants, and visible dust particles as compared to IQAir HealthPro air purifier, thanks to its V5-Cell filter.

The 5 pound adsorbent material in the filter is by and large alumina and activated carbon which traps chemicals, odors, gases, and VOCs.

IQAir HealthPro Plus Air Purifier with its new edition fan delivers up to 300 CFM (cubic feet per minute) of quality air. Its CADR rating enables cleaning 1,125 square feet twice per hour.

Apart from the CADR rating, we think its 3-stage filtration system makes it worth the cost. The prefilter is the PreMax filter which helped us to make the hospital air more breathable by trapping larger pollutants like dust particles.

We think what made IQAir HealthPro Plus to the top of our list and not Alen BreatheSmart 75i, its competitor, is because of its HyperHEPA filter, which is an H13-grade HEPA filter that traps airborne particles of 0.003 microns with an efficiency of up to 99.5%.

The HyperHEPA filters of IQAir HealthPro Plus make them 100-fold more effective than ordinary HEPA filters.

During our review, we found that the air purifier just needs an hour to leave clean and crisp air. Despite the filters being expensive, it is worth buying. We only felt the need to change the filters after using it for 17 months on its max setting of 8 to 11 hours daily.

After 6 Months of Use: Even Though we had to compromise on its casters as they came off after a month or so, we were extremely delighted to see how our team member got rid of allergies and morning flu within no time.

The only flaw that made us gave it 4.8 stars is its three filters that fits in together and needs replacement even if one fills up. However, since its filters cost much less than other air purifiers offering the same features, it is totally worth investing in it.

  • HyperHEPA filter optimally removes ultrafine particles
  • Ideal for gas and odor filtration
  • User efficient, programmable timers, six-level fan speeds
  • 3D UltraSeal reduces risk of air leakage
  • 10-year warranty
  • Expensive
  • Lacks air quality sensor

2. Medify MA-40 Air Purifier

Medify MA 40 Air Purifier APM 1

Even Though Medify MA-40 only covers up to 840 sq ft five times per hour, we still rank it second as our budget pick as it is capable of removing ultrafine particles on account of its H13 HEPA filters.

Along with our team, one of our members personally bought it for his working nurse wife when covid-19 was at its peak. Not only he appreciated how it had improved her allergies just within a few days, but its overall look too.

This high-grade medical air purifier arrives in a glossy, modern box-shaped design that adds to the look and feel of your indoor space.

Its touch-control panels allow the user to control the air purifier. The tempered glass protecting the control panel adds up to its aesthetic design. The adjustable fan speeds, sleep mode, night mode, timer function, and especially the child lock feature on the pad up top now ensures stress-free sleep and environment for the couple.

We took the measurements, and this sleek, compact unit is 22 inches high and 9.9 inches wide with a depth of 10.9 inches, just about the size of a mid-sized table. However, it is not bulky and, thus, easy to move around and make room for other hospital accessories.

The only flaw we found in using Medify MA-40 in a small room was its slight buzzing noise at its highest setting; it is most suited for larger rooms.

The only flaw we found in using Medify MA-40 in a small room was its slight buzzing noise at its highest setting; it is most suited for larger rooms.

On a comparative scale of 5, we rate Medify MA-40 4.8, considering it offers more features and a higher coverage area and CADR at a smaller price than the other purifiers mentioned.

Its 3-stage filtration system, including an H13 HEPA filter, makes it one of the best medical-grade air purifiers. We ran it for six months and found that:

The first stage includes the pre-filter, which helps us trap large particles, hair, and fibers.

The H13 HEPA filter lies next to it, which filters up to 99.9% of particles ranging between 0.1 to 0.3 microns in size. Thus, any dust, smoke, bacteria, or virus within the hospital premises are trapped in the second stage.

However, we still found some traces of cigarette smoke using a high-end smoke meter.

The third stage uses an activated carbon filter that removes foul odors, VOCs, and formaldehyde.

We turned on the optional ionizer too, which produces negative ions aiding in cleaning and freshening the indoor air and studies have shown that negative ions can be particularly effective at it.

Modify MA-40 covers up to 840 sq ft five times per hour.

You can read a more in-depth review of Modify MA-40 here.

After 6 Months of Use: Considering its cost, this unit has done wonders in making a difference in the coughing of our team member’s wife, a nurse, who now is determined to get a few installed at their local hospital too. It was a bit difficult to find the replacement filter as the manual does not provide a clear replacement part number.
  • Aesthetic and compact design
  • Optimal performance
  • Removes odor effectively
  • Quality manufacturing
  • Ideally cleans upto 420 sq. ft. within 15 mins
  • Lacks air quality sensor
  • Noisy when operating

3. Okaysou AirMax 8L Air Purifier


In narrowing down the options for the best medical-grade purifier, you can’t possibly overlook Okaysou Ultra Duo Filtration Air Purifier.

Thanks to its ultra-advanced quiet technology, turbine motor, and 5-stage filtration, we feel it is an excellent contender for your clinical setting and bedroom. It is compact and small enough to sit on the bedside table easily.

Why did Okaysou make it to our top 7 list? It carries FCC, CARB, ETL, and even CE certifications and comes in an attractive white color that goes well with the indoor aesthetics of our homes and hospitals.

The air purifier was super easy to assemble; all we had to do was remove the plastic, remove two filters (one black and one white), and plug it in.

Its 3-in-1 filter combines a mesh pre-filter, an antibacterial filter, and an H13 HEPA filter designed to trap all contaminants as small as 0.3 microns. It even removed dog dander from the air, making the air fresh and breathable after a long time.

As the next layers of filtration, we feel the combination of honeycomb pelletized activated carbon and cold catalyst filter in a 2-in-1 filter make the air purifier even more effective against odorous pollutants.

The team member checking and reviewing its performance breathed a sigh of relief when it worked for him in getting rid of the fish smell; his wife loves cooking it almost every other day.

We tested the air purifier in a 180 square feet room and concluded that the purifier could easily serve small to medium-sized rooms. The air purifier had a weird plastic smell, which subsided after a few weeks.

The 5 filtration stages and the quiet operation are the strongholds of the Okaysou AirMax8L. At just 22dB at a high CADR of 125 cfm, it is perfect for medical settings/clinics.

We give the air purifier a 4.8 rating for its bonus of white noise and covering up any ambient noise in the room.

After 6 Months of Use: The team member is now finally able to get rid of his allergies. The filters are pretty easy to find and affordable; ensuring purchase of Okaysou was worth it. The tester is thinking of buying one more for the office area.
  • Low noise profile ensure undisturbed working
  • 5 stage filter for optimal performance
  • Child lock and sleep mode ensures seamless performance
  • 5-year warranty with lifetime support
  • High stage filtration for a small motor
  • Low CADR

Also Read: 5 Best Air Purifier for Litter Box Smells in 2022

4. Medify MA-14 Air Purifier

Medify MA 14 Air Purifier

Regarding the best medical-grade air purifier for hospitals, Medify is an excellent choice as their MA-14 air cleaner also makes the top of our list because of its handy size and advanced tech.

This air purifier contains an H13 HEPA filter essential for cleaning the hospital environment. Modifying MA-14 cleans the air effectively without going out of pocket.

This is for you if you want an air purifier under $100.

This desktop-grade air purifier arrives with a 3-layer filter cartridge consisting of a Pre-filter, an H13 HEPA filter, and an activated carbon filter. Make sure you pull off the plastic before using the cartridge. Like many people, we also didn’t pull it out first as it wasn’t mentioned in the manual, plus the plastic was barely visible. This is one of the reasons why people complan that sometimes air purifier smells like plastic.

The first stage in the 3-in-1 physical filter is the pre-filter. It helps us with dust, lint, hair, and fibers from the air, reducing any risk of allergies. The second stage, the H13 HEPA filter, traps down particles to 0.3 microns. The air purifier dealt with smoke particles, dust, and mold spores excellently during our testing.

After the H13 filters come the activated carbon filter, which eliminates light odors. Modify MA-14 remains ideal for placing on the tabletop because it weighs 5 pounds.

These air purifiers operate quietly at 33dB when set to sleep mode, thus helping us keep the patients in the hospital at peace.

According to our testing, Modify MA-14 is best for cleaning up to 200 square feet five times per hour, and we will rate it 4.6 for its efficacy.

After 6 Months of Use: I saw a clear difference in indoor air quality and especially my health. The chest pain due to heavy smog has subsided and now I can breathe without any difficulty, thanks to Medify MA-14.
  • H13 HEPA filter cleans air
  • Aesthetic design
  • Portable, Compact yet powerful
  • Ideal for countertops
  • Easy controlling and replacement
  • Costly filter replacement
  • Low CADR ratings

5. LEVOIT Vital 100 Air Purifier

LEVOIT Air Purifier

The next air purifier made to our list of best medical-grade air purifiers is the Levoit Vital 100 Air Purifier. Its H13 HEPA filters, compact design, and low noise profile made us pick it for medical premises.

On a comparative scale of 5 from Okaysou AirMax, we will rate it 4.3. Okaysou AirMax beats Levoit Vital 100 in the air filtration stages, which means more refreshable air. However, Levoit Vital 100 is nothing less than Okaysou AirMax; we could trap any dirt, dust, pollen, and pet dander in the room on the prefilters without hassle.

As instructed in the manual, we washed the prefilters to eliminate the entrapped particles without compromising the filter life.

The medical-grade H13 HEPA filter captures 99.97% of airborne particles of 0.3 microns. This filter helped us eliminate dust, mold spores, bacteria, and smoke particles effectively.

Its honeycomb-activated carbon filter plays a crucial role in neutralizing unpleasant medication odors, smoke, and VOCs.

This air purifier has a CADR of 130 cfm, thus effectively cleaning 300 square feet of the room twice an hour.

At the lowest fan setting, the air purifier makes a noise of 23 dB which adds up to its merits. Even on its highest setting, it only makes a noise like a window unit air conditioner.

Concluding all its kicks and flaws, we give this air purifier a 4.3 rating, recommending it best for bedrooms and lounges. The air purifier is sleek and extremely lightweight, ideal for traveling.

After 6 Months of Use: Our tester appreciates how he now spends less on inhalers and totally rely on Levoit Vital 100 to get relief from sinus.

However, it is not powerful enough to cover a large area and he can still speck of dust a little far from where the air purifier is placed.

  • 100% ozone free
  • Washable pre-filter
  • Ideal for allergic persons
  • Sleek and compact design
  • Low noise profile
  • Appropriate for small and medium areas
  • Lacks child/pet lock

6. Alen BreatheSmart 75i Air Purifier

Alen BreatheSmart 75i

Alen is at the forefront of air purifiers in 2022, and their popularity has skyrocketed recently. It won’t be wrong if we call this piece an epitome of beauty; the 75i perfectly showcases Alen’s design and manufacturing prowess.

Alen BreatheSmart 75i is Alen’s latest model and is better than its precursor Alen BreatheSmart Classic regarding coverage area and purification process.

We found the latest model large but still better than its precursors as its large body packs impeccable features like greater filter life of 12 to 15 months and less power use (45W). We had to change the filter in Alen’s Classic model after every nine months, which took a toll on our budget, inclusive of the large electricity bill it generates as it runs on 60W.

The purifier is extremely quiet and has an outstanding CADR rating of 400, making it ideal for medical-grade requirements.

Alen has opted for a simplistic design that ensures a high clean air delivery rate and the color choice of black and white makes it ideal for a lounge or any indoor setting.

Alen uses an all-in-one filter design that needs replacement once a year and houses a mix of pre-filter, H13 HEPA filter, and activated carbon filter layers.

If you don’t want to take a risk and want all-out protection, then opting for the Heavy Odor Filter would be the best bet as our testers say it can easily handle pet dander, VOCs, chemical fumes, allergens, microbes and has an efficiency rating of 99.99% for particles down to a size of 0.3 microns.

The high CADR also translates to higher coverage, and the 75i can easily cater to the purification needs of up to 1300 sq. ft. of space.

The purifier can filter the indoor air 2 times in a 1300 sq. ft. space or 5 times in a space under 1000 sq. ft.

We don’t have to worry about adjusting the fan speed repeatedly as the air cleaner’s auto mode will detect changes in the air quality and adjust the speed accordingly. The purple ring shows the worst air quality, while blue is for the best air quality.

The best things about the 75i that help it stand out are the quiet operation and stellar energy consumption. Perhaps the only downside to the Alen Breathesmart 75i is the high initial purchase cost and the expensive annual filters that cost as much as $100.

But when this cost is compared with the performance of some other purifiers, you’ll be surprised that cheaper models can feel more expensive when cleaning a room of comparable size.

IQAir HealthPro Plus is a top pick, but Alen BreatheSmart 75i is nothing less and ranks 4.1 on a scale of 5. Even though Alen has a lesser CADR than IQAir, it covers more space to get more crisp and fresh air over a larger area. So, Alen is a go-to choice if, like us, you want to get rid of basic odors and allergens while staying within the budget.

The Breathesmart 75i is a simple solution to even the harshest indoor air quality problems and will provide medical-grade protection against airborne allergens and other contaminants.

After 12 Months of Use: What made Alen different from other purifiers is its less overall replacement cost of the filter; we just replaced it only once in an year. After testing it fully and considering its remarkable performance and affordability, we gifted it to a nearby local hospital as a goodwill.
  • Outstanding 400 CADR rating; achieved with only 347 CFM airflow
  • Up to 1,300 sq ft coverage
  • The quietest large air purifier
  • H13 medical-grade HEPA filters that last for 12 months
  • 99.99% efficient air cleaning
  • Low maintenance costs
  • Energy-efficient fan results in a lower electricity bill
  • Smart Sensor technology
  • Higher initial cost of 75i (well balanced out by long term savings on HEPA filters)

7. HATHASPACE HSP002 HEPA 2.0 Smart Air Purifier


All manufacturers bring a different take on air purification techniques and use different filtration methods to get results. HATHASPACE brings 5 filtration stages, including a cold catalyst filter that makes it an excellent air purifier for a medical setting.

The HSP002 isn’t just a great purifier; it is also aesthetic. The purification starts with a washable pre-filter that doesn’t require replacement and can be washed when needed.

Considering the convenience HATHSPACE offers at a reasonable price in the long run, the air purifier deserves a rating of 4.5.

The pre-filter is followed by a replaceable H13 HEPA filter that easily handles 99.95% of airborne contaminants down to a size of 0.1 microns.

Even Though this air purifier is reasonably working, there should have been more at this price level. It doesn’t help to get complete riddance from dust.

You don’t have to worry about chemical or medicinal odors as the HEPA filter is followed by an activated carbon filter that helps us trap odors while also neutralizing VOCs, among other harmful gaseous irritants, making the air breathable and fresh.

HATHASPACE carefully selected the filtration techniques and the ozone-free filtration, unlike competitors’ offerings, making it an excellent choice for indoor space.

Since Ozone is a known irritant, this 100 percent ozone-free air purifier has done wonders for us, proving itself to be friendly for our pets, children, and especially the elderly with allergies or asthma.

The coupling of 4 filters into one replaceable filter ensures that no contaminant particles can escape the purifier. The single replacement filter has the polypropylene pre-filter, H13 HEPA filter, activated carbon filter, and cold catalyst filter.

This H13 HEPA filter removes 99.95% of particles between 0.1 to 0.3 microns. These include ultrafine dust, traffic pollutants, tobacco smoke particles, and microorganisms.

Built with activated carbon pellets, the honeycomb carbon filter traps household odors. Last, we have the cold catalyst filter. This filter helps us target VOCs and harmful chemicals commonly found in household cleaning products.

The manufacturer has worked on its evolution, making it truly stand out from its precursor HSP001. It made it to our list of top 7 out of 15 air purifiers we reviewed because of the upgradation of the filter from H11 to H13, the greater number of fan speeds i.e, 4, and larger coverage area than its precursor (750 sq. ft).

We found it easier to track indoor air quality by including user convenience features like filter change indicator and air quality index.

Hathaspace HSP002 has a maximum CADR of 200 cfm, capable of cleaning a large 1500 square feet space twice per hour, suitable for large areas like bedrooms, living rooms, and even basements.

Even though the air purifier can cover a maximum of 1500 sq ft, we believe Alen performs better on greater filter life, higher CADR, and circulating cleaner air.

Out of the box, its minimalistic and sleek design complements our interiors well. We can compromise on its tall size considering its excellent quiet operation. The powerful fan adjusts itself to maintain optimum air quality.

After 12 Months of Use: There is not a better proof of its remarkable performance than seeing our daughter gradually improving from the cough just within a week and allergies in a few months. The air purifier is large but has served well on its purpose.
  • Comes with 5-stage physical filters
  • Washable and permanent pre-filter
  • Whisper quiet sleep mode
  • It has a smart air quality sensor
  • Features a beautiful, sleek touch panel
  • Ideal for large living spaces
  • High filter replacement cost
  • Has carrying handle

Also Read: Do You Put Water In A Dehumidifier? (Explained)


What kind of air purifiers do hospitals use?

Hospitals and other medical facilities employ air purifiers with advanced HEPA filters like the one listed above. According to studies, a HEPA filter allows air purifiers to filter out contaminants with 99.97-99.99% efficiency.

Do medical-grade air purifiers work for Covid?

Medical-grade air purifiers with multiple purification stages can trap and neutralize the COVID-19 virus. While the protection offered by the air purifier is not fool-proof, it still reduces the chance of contracting the virus.


We hope this guide sharing our personal experience has helped you cut down options to choose between the Best Medical Grade Air Purifiers available on the market. As you’d know by now, all purifiers and contaminants in a medical facility are different.

If you’re choosing an air purifier that provides medical-grade protection, you must ensure that the air cleaner brings an H13 HEPA filter alongside other filters. UV protection and high carbon content are welcome additions, but the absence of H13 will make the whole package ineffective.

No matter which one of the seven purifiers you go for, according to our testing, each is equipped with unique features and excellent working that will keep even the tiniest air pollutants at bay and provide significant health improvements within a few hours installing them.