7 Best Medical Grade Air Purifier in 2022

Medical-grade air purifiers can filter out at least 99.97% of airborne contaminants, allergens, respiratory irritants, and can even neutralize odors. They offer hospital-grade protection that makes them perfect for people with severe allergies or medical conditions.

With a team of five members, we’ve done the research for you and have tested 15 air purifiers and each for minimum of 4 weeks to prepare a shortlist of the best hospital-grade air purifiers.

Each manufacturer adds its own technology to the H13 HEPA filter to offer more complete protection. According to studies and manufacturing guidelines, the H13 HEPA filter can easily filter 99.95% of airborne contaminants, making it an ideal choice for hospital-grade protection. Let’s take a look at what each purifier brings to the table.

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Update: We have updated our review based on 6 month use so you can find more insight on how each one performs on the long run.

Best Medical Grade Air Purifier List (Comparison table)

In a hurry? This table will equip you with all the necessary information you need to make the ultimate decision. Read on to get a better insight on our first hand-on experience and more complete in-depth analysis of each purifier.

CADR: 776 cfm
Filteration Stages: 4
Area Coverage: 1125 sq. ft.
Budget pick
Medify MA-40
CADR: 224 cfm
Filteration Stages: 3
Area Coverage: 840 sq. ft.
Okaysou Air Purifier
CADR: 210 cfm
Filteration Stages: 5
Area Coverage: 320 sq. ft.
CADR: 71 cfm
Filteration Stages: 3
Area Coverage: 200 sq. ft.
LEVOIT Air Purifier
CADR: 130 cfm
Filteration Stages: 3
Area Coverage: 300 sq. ft.
Alen BreatheSmart 75i
CADR: 347 cfm
Filteration Stages: 4
Area Coverage: 1300 sq. ft.
CADR: 265 cfm
Filteration Stages: 5
Area Coverage: 1500 sq. ft.

1. IQAir HealthPro Plus Air Purifier

IQAir HealthPro Plus Air Purifier

If you’re looking for the best medical grade H13 HEPA air purifier, IQAir HealthPro Plus is for you. Thanks to its V5 cell filter, we were able to get rid of the smell of our freshly painted clinic in just within half an hour.

Through customer satisfaction and quality manufacturing, IQAir gains trust among other brands in the market. Along with the optimal air cleaning credited to the proprietary Even Flow Diffuser technology, the premium Swiss touch and design gives the air purifier a 4.8 rating.

The EvenFlow Diffuser technology ensures 320-degree clean air delivery to breathe.

We found it perfect for the hospital settings considering how it effectively removed the unpleasant odors of the medicines prevailing in the hospital environment.

Now that the unit is extremely bulky and large, the size of a mid-sized table, it was hard to move it around and find a perfect place for it. We lastly decided to place it where the patient crowd is the most.

On comparison with its precursor, we found IQAir HealthPro Plus better, considering how the air purifier has evolved. 

We found the plus version more effective in cleaning odors, gaseous pollutants, and visible dust particles as compared to IQAir HealthPro air purifier, thanks to its V5-Cell filter.

The 5 pound adsorbent material in the filter is by and large alumina and activated carbon which traps chemicals, odors, gases, and VOCs.

IQAir HealthPro Plus Air Purifier with its new edition fan delivers up to 300 CFM (cubic feet per minute) of quality air. Its CADR rating enables cleaning 1,125 square feet twice per hour.

Apart from the CADR rating, we think its 3-stage filtration system makes it worth the cost. The prefilter is the PreMax filter which helped us to make the hospital air more breathable by trapping larger pollutants like dust particles.

We think what made IQAir HealthPro Plus to top of our list and not Alen BreatheSmart 75i, its competitor, is because of its HyperHEPA filter, which is an H13-grade HEPA filter that traps airborne particles of 0.003 microns with an efficiency of up to 99.5%.

The HyperHEPA filters of IQAir HealthPro Plus make them 100 fold more effective than ordinary HEPA filters.

During our review we found that the air purifier just needs an hour to leave clean and crisp air. Despite the filters being expensive, it is worth buying. We only felt the need to change the filters after using it for 17 months on its max setting 8 to 11 hours daily.

After 6 Months of Use: Even Though we had to compromise on its casters as they came off after a month or so, we were extremely delighted to see how our team member got rid of allergies and morning flu within no time.

The only flaw that made us gave it 4.8 stars is its three filters that fits in together and needs replacement even if one fills up. However, since its filters cost much less than other air purifiers offering the same features, it is totally worth investing in it.

  • HyperHEPA filter optimally removes ultrafine particles
  • Ideal for gas and odor filtration
  • User efficient, programmable timers, six-level fan speeds
  • 3D UltraSeal reduces risk of air leakage
  • 10-year warranty
  • Expensive
  • Lacks air quality sensor

2. Medify MA-40 Air Purifier

Medify MA-40 Air Purifier

Even Though Medify MA-40 only covers up to 840 sq ft five times per hour, we still rank it second as our budget pick as it is capable of removing ultrafine particles on account of its H13 HEPA filters.

Along with our team, one of our members personally bought it for his working nurse wife when covid-19 was at its peak. Not only he appreciated how it has improved her allergies just within a few days but its overall look too.

This high-grade medical air purifier arrives in a glossy, modern box-shaped design that adds to the look and feel of your indoor space.

Its touch control panels allow the user to control the air purifier. The tempered glass protecting the control panel adds up to its aesthetic design. The adjustable fan speeds, sleep mode, night mode, timer function, and especially the child lock feature on the pad up top now ensures stress-free sleep and environment to the couple.

We took the measurements and this sleek, compact unit is 22 inches high and 9.9 inches wide with a depth of 10.9 inches, just about the size of a mid-sized table. However, it is not bulky and thus, easy to move around and make room for other hospital accessories.

The only flaw we found in using Medify MA-40 in a small room was its slight buzzing noise at its highest setting; it is most suited for larger rooms.

The only flaw we found in using Medify MA-40 in a small room was its slight buzzing noise at its highest setting; it is most suited for larger rooms.

On the comparative scale of 5, we rate Medify MA-40 4.8, considering it offers more features and higher coverage area and CADR at a smaller price than other purifiers mentioned.

Its 3-stage filtration system that includes an H13 HEPA filter, makes it one of the best medical grade air purifiers. We ran it for 6 months and found that:

The first stage includes the pre-filter which helps us traps any large particles, hair, and fibers.

The H13 HEPA filter lies next to it, which filters up to 99.9% of particles ranging between 0.1 to 0.3 microns in size. Thus, any dust, smoke, bacteria, or virus within the premises of the hospital are trapped in the second stage.

However, we still found some traces of cigarette smoke using a high-end smoke meter.

The third stage uses an activated carbon filter that removes foul odors, VOCs, and formaldehyde.

We turned on the optional ionizer too which produces negative ions aiding in cleaning and freshening the indoor air and studies have shown that negative ions can be particularly effective at it.

Medify MA-40 covers up to 840 sq ft five times per hour.

You can read a more in-depth review of Medify MA-40 here.

After 6 Months of Use: Considering its cost, this unit has done wonders in making a difference in the coughing of our team member’s wife, a nurse, who now is determined to get a few installed at their local hospital too. It was a bit difficult to find the replacement filter as the manual does not provide a clear replacement part number.
  • Aesthetic and compact design
  • Optimal performance
  • Removes odor effectively
  • Quality manufacturing
  • Ideally cleans upto 420 sq. ft. within 15 mins
  • Lacks air quality sensor
  • Noisy when operating

3. Okaysou AirMax 8L Air Purifier

Okaysou AirMax Air Purifier

In narrowing down the options for the best medical grade purifier, you can’t possibly overlook Okaysou Ultra Duo Filtration Air Purifier.

Thanks to its ultra-advanced quiet technology, turbine motor, and 5 stage filtration, we feel it is an excellent contender for your clinical setting and bedroom. It is compact and small enough that it easily sits on the bedside table.

Why did Okaysou make it to our top 7 list? It carries FCC, CARB, ETL, and even CE certification and comes in an attractive white color that goes well with the indoor aesthetics of our home and hospitals.

The air purifier was super easy to assemble, all we had to do was take out the plastic, remove two filters (one black and one white) and plug it in.

Its 3-in-1 filter is a combo of a mesh pre filter, antibacterial filter, and an H13 HEPA filter designed to trap all contaminants as small as 0.3 microns.

As the next layers of filtration, we feel the combination of honeycomb pelletized activated carbon and cold catalyst filter in a 2-in-1 filter make the air purifier even more effective against odorous pollutants.

The team member checking and reviewing its performance breathed a sigh of relief when it actually worked for him in getting rid of fish smell, his wife loves cooking it almost every other day.

We tested the air purifier in a 180 square feet room and concluded that the purifier can easily serve from small to medium-sized rooms. The air purifier came with a weird plastic smell, which subsided after a few weeks.

The 5 filtration stages and the quiet operation are the strongholds of the Okaysou AirMax8L. At just 22dB at a high CADR of 125 cfm, it is perfect for medical settings/clinics.

We give the air purifier 4.8 rating for its added bonus of white noise and covering up any ambient noise in the room.

After 6 Months of Use: The team member is now finally able to get rid of his allergies. The filters are pretty easy to find and affordable; ensuring purchase of Okaysou was worth it. The tester is thinking of buying one more for the office area.
  • Low noise profile ensure undisturbed working
  • 5 stage filter for optimal performance
  • Child lock and sleep mode ensures seamless performance
  • 5-year warranty with lifetime support
  • High stage filtration for a small motor
  • Low CADR

Also Read: 5 Best Air Purifier for Litter Box Smell in 2022

4. Medify MA-14 Air Purifier

Medify MA 14 Air Purifier

When it comes to the best medical-grade air purifier for hospitals, Medify is an excellent choice as their MA-14 air cleaner also makes the top of the list.

This air purifier contains an H13 HEPA filter which is essential to clean the hospital environment. Medify MA-14 cleans the air effectively without going out of pocket.

If you’re looking for an air purifier under $100, then this is for you.

This desktop-grade air purifier arrives with a 3-layer filter cartridge consisting of a Pre-filter, H13 HEPA filter, and an activated carbon filter.

The first stage in the 3-in-1 physical filter is the Pre-filter which removes dust, lint, hair, and fibers from the air. The second stage is the H13 HEPA filter which traps particles down to 0.3 microns, for instance, smoke particles, dust, and mold spores.

After the H13 filters come to the activated carbon filter which eliminates light odors. Medify MA-14 remains ideal for placing on the tabletop on account of its 5 pounds of weight.

These air purifiers operate quietly at 33dB when set to sleep mode, thus keeping the patients in the hospital at peace.

Medify MA-14 cleans up to 200 square feet five times per hour.

  • H13 HEPA filter cleans air
  • Aesthetic design
  • Portable, Compact yet powerful
  • Ideal for countertops
  • Easy controlling and replacement
  • Costly filter replacement
  • Low CADR ratings

5. LEVOIT Vital 100 Air Purifier

LEVOIT Air Purifier

Our next pick on the list of best medical-grade air purifiers is the Levoit Vital 100 Air Purifier. Its H13 HEPA filters, compact design, and low noise profile make it a good pick for medical premises.

Any dirt, dust, pollen, and pet dander in the room get trapped on the prefilters. To get rid of the entrapped particles, Pre-filters are washed without compromising the filter life.

The medical-grade H13 HEPA filter captures 99.97% of airborne particles of 0.3 microns. These main particle filters effectively trap dust, mold spores, bacteria, and smoke particles.

The honeycomb activated carbon filters play a crucial role in neutralizing unpleasant medication odors, smoke, and VOCs.

This air purifiers has a CADR of 130 cfm, thus effectively cleaning 300 square feet of the room twice an hour.

At the lowest fan setting, the air purifier makes a noise of 23 dB which adds up to its merits.

  • 100% ozone free
  • Washable pre-filter
  • Ideal for allergic persons
  • Sleek and compact design
  • Low noise profile
  • Appropriate for small and medium areas
  • Lacks child/pet lock

6. Alen BreatheSmart 75i Air Purifier

Alen BreatheSmart 75i

Alen is at the forefront of air purifiers in 2022 and their popularity has skyrocketed during recent times. The 75i perfectly showcases the design and manufacturing prowess of Alen.

The purifier is extremely quiet and brings an outstanding CADR rating of 400 making it an ideal purifier for any medical-grade requirements.

Alen has opted for a simplistic design that ensures a high clean air delivery rate and the color choice of black and white makes it ideal for any indoor setting.

Alen uses an all-in-one filter design that needs replacement once a year and houses a mix of pre-filter, H13 HEPA filter, and activated carbon filter layers.

If you don’t want to take a risk and want all-out protection then opting for the Heavy Odor Filter would be the best bet as it can easily handle pet dander, VOCs, chemical fumes, allergens, microbes, and has an efficiency rating of 99.99% for particles down to a size of 0.3 microns.

The high CADR also translates to higher coverage and the 75i can easily cater to the purification needs of up to 1300 sq. ft. of space.

The purifier can filter the indoor air 2 times in a 1300 sq. ft. space or 5 times in a space under 1000 sq. ft.

You don’t have to worry about adjusting the fan speed again and again as the auto mode on the air cleaner will detect changes in the air quality and adjust the speed accordingly. The purple ring shows the worse air quality while blue is for the best air quality.

The best things about the 75i that help it stand out are the quiet operation and that too at stellar energy consumption.

Perhaps the only downside to the Alen Breathesmart 75i is the high initial cost of purchase and the expensive annual filters that can cost as much as $100.

But when this cost is compared with the performance of some other purifiers, you’ll be surprised that cheaper models can actually feel more expensive when cleaning a room of comparable size.

All in all, the Breathesmart 75i is a simple solution to even the harshest indoor air quality problems and will provide medical-grade protection against airborne allergens and other contaminants.

  • Outstanding 400 CADR rating; achieved with only 347 CFM airflow
  • Up to 1,300 sq ft coverage
  • The quietest large air purifier
  • H13 medical-grade HEPA filters that last for 12 months
  • 99.99% efficient air cleaning
  • Low maintenance costs
  • Energy-efficient fan results in a lower electricity bill
  • Smart Sensor technology
  • Higher initial cost of 75i (well balanced out by long term savings on HEPA filters)

7. HATHASPACE HSP002 HEPA 2.0 Smart Air Purifier


All manufacturers bring a different take on air purification techniques and make use of different filtration methods to get results. HATHASPACE brings 5 filtration stages including a cold catalyst filter that makes it an excellent air purifier for a medical setting.

The HSP002 isn’t just a great purifier, it is aesthetic as well. The purification starts with a washable pre-filter that doesn’t require replacement and can be washed when needed.

The pre-filter is followed by a replaceable H13 HEPA filter that handles 99.95% of airborne contaminants down to a size of 0.1 microns with ease.

You don’t have to worry about any chemical or medicinal odors as the HEPA filter is followed by an activated carbon filter that can trap odors while also neutralizing VOCs among other harmful gaseous irritants.

HATHASPACE carefully selected the filtration techniques and the ozone-free filtration, unlike some offerings from competitors, make it an excellent choice for indoor space.

Ozone is a known irritant 100 percent ozone-free, which is friendly for pets, child or someone with allergies or asthma.

The coupling of 4 filters into the 1 replaceable filter ensures that none of the contaminant particles can escape the purifier. The single replacement filter has the polypropylene pre-filter, H13 HEPA filter, activated carbon filter, and a cold catalyst filter.

This H13 HEPA filter removes 99.95% of particles which are between 0.1 to 0.3 microns. These include ultrafine dust, traffic pollutants, tobacco smoke particles, and microorganisms.

Build with activated carbon pellets; the honeycomb carbon filter traps household odors. Last, we have the cold catalyst filter. This filter targets VOCs and harmful chemicals commonly found in household cleaning products.

Hathaspace HSP002 has a maximum CADR of 200 cfm, capable of cleaning a large 1500 square feet space twice per hour, suitable for large areas like bedrooms, living room, and even basement.

  • Comes with 5-stage physical filters
  • Washable and permanent pre-filter
  • Whisper quiet sleep mode
  • It has a smart air quality sensor
  • Features a beautiful, sleek touch panel
  • Ideal for large living spaces
  • High filter replacement cost
  • Has carrying handle

Also Read: Do You Put Water In A Dehumidifier? (Explained)


What kind of air purifiers do hospitals use?

Hospitals and other such medical facilities employ air purifiers with advanced HEPA filters like the one listed above. According to studies, a HEPA filter allows the air purifiers to filter out contaminants with 99.97-99.99% efficiency.

Do medical-grade air purifiers work for Covid?

Yes, medical-grade air purifiers with multiple purification stages can trap and neutralize the COVID-19 virus. While the protection offered by the air purifier is not fool-proof, it still reduces the chance of contracting the virus.


We hope this guide helped you choose between the Best Medical Grade Air Purifiers available on the market. As you’d know by now, all purifiers are different and so are the contaminants in a medical facility.

If you’re choosing an air purifier that provides medical-grade protection, you’ll need to make sure that the air cleaner brings an H13 HEPA filter alongside other filters. UV protection and high carbon content are welcome additions but the absence of H13 will make the whole package ineffective.

We’ve listed the best air purifiers on the market that will keep even the tiniest air pollutants at bay and will provide significant health improvements within a few hours of installing them.