5 Best Air Purifier for Eczema in 2022

Atopic dermatitis a.k.a Eczema can be very annoying and periodic flare-ups can actually hamper your social life. Despite all the advancements in technology and medicine, researchers are still divided when it comes to allergies.

Thankfully, there is a simple solution that doesn’t have any side effects. Numerous studies have pointed out the efficiency of air filtration and purification against eczema. So if you’re one of those people that suffer from eczema and your life is suffering from allergy flare-ups you’re in the right place.

This guide will help you understand if air purifiers can help against chronic conditions like eczema and which one is the best choice for you.

Does Air Purifier Help With Eczema?

Yes, according to official stats from the EPA, an air purifier with a HEPA filter can effectively remove 99.97% of skin and respiratory irritants in the air, helping control the allergy flare-ups and improving indoor air quality at the same time.

Dust, mites, pollens, and dander all contribute to eczema in one way or the other and while researchers are divided as to what can cause the flare-ups, removal of these and other pollutants from the air has shown promising results.

Air purifiers not only remove allergy triggers but also tackle dangerous VOCs, pet allergens, dust, respiratory allergens, molds, odors, and even mycotoxins from the indoor air.

However, not all air purifiers are efficient against eczema. Those with just a basic filter won’t be able to trap the minute particles that irritate the skin. The best air purifiers use a combination of a Pre-filter that traps larger particles, a HEPA, or true HEPA filter that traps the smallest of particulate matter, and an activated carbon filter that handles the gaseous content including VOCs.

So, which air purifier is the best for eczema? Let’s look at the best air purifiers on the market that can help keep allergens in check and offer the best performance.

Best Air Purifier for Eczema

In a hurry? The comparison table below has all the information you’ll need to make the right decision. Read on for a more detailed review.

Top pick
Filtration Stages: 5
UV-C Light: Yes
Coverage Area: 180 sq. ft.
Editor’s Pick
Winix 5500-2 Air Purifier
Filtration Stages: 4
UV-C Light: No
Coverage Area: 350 sq. ft.
Alen BreatheSmart Classic
Filtration Stages: 3
UV-C Light: No
Coverage Area: 1100 sq. ft.
Filtration Stages: 5
UV-C Light: No
Coverage Area: 400 sq. ft.
Okaysou Air Purifier
Filtration Stages: 3
UV-C Light: No
Coverage Area: 320 sq. ft.

1. GermGuardian AC5250PT Air Purifier

GermGuardian AC5250PT Air Purifier

GermGuardian has been around for quite some time now and their air purifiers offer medical-grade protection against most common allergens and odors. The AC5250PT is no different. The purifier was specifically designed to tackle pet-related issues and can hence easily filter out even the finest contaminants that can lead to eczema.

The 5250PT features a 5-stage filtration system in a sleek, modern design, and the purifier improves on many aspects of the simpler AC5250. The defense against eczema-causing allergens starts with a permanent mesh filter that is paired with a charcoal pre-filter.

The charcoal/activated carbon filter can easily remove VOCs, fumes, and dangerous chemicals that might irritate the skin. The pre-filter works in combination with a true HEPA filter that can trap even the smallest of skin irritants.

The HEPA filter is EPA certified and can trap particles down to a size of 0.3 microns with a 99.97% accuracy. Although many purifiers offer a similar approach, the GermGuardian 5250PT goes an extra step and has added a UV-C light chamber.

The UV-C light chamber can destroy microbial DNA that can irritate the skin that might lead to eczema. Eczema can also flare up because of mold spores in the air, the UV-C chamber filters and kills the mold DNA, slowing and stopping mold growth, and can even kill coronavirus according to studies.

GermGuardian AC5250PT is efficient at what it does and can conveniently trap eczema-causing allergens in small to mid-sized rooms.

Replaceable Filter Life: 6-8 months

Warranty: 5 years

Award: Best Budget Choice

  • Multiple-stage filtration purifies the indoor air and removes skin allergens
  • UV-C light destroys microbial DNA
  • Efficient operation saves on operational costs
  • Can get a bit loud at times
  • Lack of smart and autonomous features

2. Winix 5500-2 Air Purifier

Winix 5500-2

Winix is synonymous with durability and efficiency. With so many different models on offer, it is simply one of the best air purifier manufacturers out there. The Winix 5500-2 is an excellent air purifier that builds on the success of the hugely popular 5500 before it and the mid-tier 5300-2.

The Winix 5500-2 improves over the outgoing WInix 5500 and adds smart features to the excellent 4-stage filtration system. The pre-filter and the True HEPA filter trap both large-sized and small particles that can lead to skin irritation including hair, pet dander, dust mites, and even bacteria down to a size of 0.3 microns with a 99.97% efficiency.

The carbon filter absorbs dangerous VOCs, harmful chemicals, and foul odors making the indoor air safer. Winix’s PlasmaWave technology acts as the 4th stage of filtration and releases negative ions that stick to the contaminants making them heavier and decreasing any chance of them staying airborne. Negative ions have proven very efficient at removing airborne contaminants according to various studies.

The 5500-2 has a respectable 240 CFM CADR that makes it efficient for larger rooms up to 360 sq. ft. The air cleaner can clean the indoor air 5 times an hour in a 360 sq. ft. setting making it an ideal option for your lounge or bedroom.

The Winix 5500-2 features an Auto mode that automatically detects if the air quality is decreasing and can adjust fan speed according to the air quality around the air purifier. This helps maintain optimal air quality even during sleep.

All in all, the Winix 5500-2 is a unique mix of excellent features, modern design, and exceptional operational costs, all at an affordable price point. Other manufacturers do offer similar features but at thrice or four times the price of Winix 5500-2.

The Winix 5500-2 can perfectly handle skin and respiratory allergens; has an affordable price tag, and brings additional features like the convenience of remote control and auto mode.

Replaceable Filter Life: 12 months

Warranty: 2 years

Award: Best Overall

  • Automatic mode makes allergen removal a seamless operation
  • Energy-star certification ensures low power consumption
  • 4-stage filtration catches particulate matter as well as odors
  • Can release traces of ozone

Also Read: 7 Best Medical Grade Air Purifier in 2022

3. Alen BreatheSmart Classic

Alen BreatheSmart Classic

Little can go wrong with the Alen BreatheSmart Classic. It is the epitome of air purification from a quality manufacturer that offers industry-leading technology in its products.

The Classic is another aesthetic and powerful design that can be paired with Alen’s BF35-VOC filter that boasts a medical-grade H13 True HEPA filter, carbon filters, and a pre-filter in one package.

The unique manufacturing process for the filters allows Alen to reach a removal efficiency of 99.99% against a particulate matter that can cause eczema-like skin conditions

In addition to eczema causing allergens, the Classic is also efficient against pollution, smoke, smog, and toxic VOCs, and can also handle wildfire smoke.

The Alen BreatheSmart Classic isn’t cheap to buy and the filter replacement costs aren’t cheap either. It can cost as much as $100 to replace the filter but the yearly replacement time makes it a bit less of a worry.

The filter can easily handle wildfire smoke and can remove the finest of particles that cause allergies. Like the Winix 5500-2, the BreatheSmart Classic also brings automatic mode and smart sensors to adjust fan speeds depending on the indoor contamination levels.

The air cleaner also has an air quality indicator up top that can show the current air quality in the room. The indicator lights up red for bad air quality and triggers the maximum fan speeds to ensure quick removal of allergens and pollutants.

At 290 CFM, it can easily cover even the largest of spaces making it an excellent whole-home air purifier that can help with eczema.

The BreatheSmart Classic doesn’t have added purification stages like some other options on the list but the complete protection it offers doesn’t need an extra stage. The only reason this purifier isn’t at the top of the list is because of the hefty price tag. It can cost almost 4 times as much as the Winix 5500-2 offers comparable performance.

Replaceable Filter Life: 6 months

Warranty: Lifetime

Award: Best for Large Spaces

  • Excellent performance
  • Higher CADR and ACH makes it an excellent choice for larger rooms
  • Lifetime warranty with active filter subscriptions
  • Loud at the highest fan speeds

Also Read: Best Air Purifier for Dorm Room in 2022

4. Hathaspace HSP002

Hathaspace HSP002

HATHASPACE offers a unique and efficient 5 stage filtration system that can purify the indoor air even in a medical setting. The purifier is beautifully designed and can easily handle eczema-causing allergies.

Hathaspace suggests changing its filter every 4 months which was a little too low for our liking but thankfully the manufacturer has included not one, but two pre-filters. The first pre-filter can be removed and is washable, making everything very seamless and easy to manage.

The pre-filter passes the indoor air onto the H13 HEPA filter that handles 99.95% of airborne contaminants down to a size of 0.1 microns with ease.

For gaseous pollutants and dangerous chemicals, the purifier has an activated carbon filter and a cold catalyst filter that ensures complete protection.

HATHASPACE’s choice of not including a UV-C chamber is to do with the unintentional production of ozone gas. Ozone is a known irritant and the HSP002 is totally ozone-free hence won’t trigger any respiratory or skin allergies.

All 4 filters are coupled into 1 and can easily handle ultrafine dust, traffic pollutants, tobacco smoke particles, and microorganisms that can flare up eczema.

Hathaspace HSP002 has a maximum CADR of 200 CFM placing it right in the middle of large space and medium-sized rooms. It can clean a large 750 square feet space twice per hour making it an excellent all-rounder that offers excellent protection and design decisions.

Replaceable Filter Life: 6 months

Warranty: 5 years

Award: Editor’s Choice

  • Comes with 5-stage physical filters
  • Washable pre-filter
  • Smart air quality sensor automatically adjusts airflow
  • Quiet operation
  • Ideal for large rooms
  • High filter replacement cost

5. Okaysou Air Purifier

Okaysou Air Purifier

The one solution to all your air environments lies within this Ultra Duo filtration system air purifier. The 5 stage physical filters embedded in Okaysou Air Purifier make it one of the best for medical settings. Its latest quiet technology, Ultra-Duo filtration system, and more advanced turbine motor make these air purifiers stand out amongst the others.

The Ultra Filter makes the air free from particles as small as 0.25 microns. The 3-in-1 Ultrafilter contains a mesh prefilter, an H13 HEPA filter, and an antibacterial filter.

The 2-in-1 Duo Filter comprises an activated carbon filter and a cold catalyst filter. The honeycomb pelletized carbon filter and catalyst filter adhere to odorous pollutants.

Okaysou AirMax8L has a CADR of 125 cfm and it cleans up to 185 square feet five times per hour. These air purifiers are effective for small to medium rooms. The low noise profile of 22dB only, makes these air purifiers fit to serve medical settings.

Okaysou AirMax8L is certified by CARB, CE, FCC, and ETL. It comes in white color which gives a decent and calming look to your room.

Replaceable Filter Life: 6 months

Warranty: 1 year

  • Suitable for medium to a small room
  • Optimal performance
  • Cost-effective
  • Quite performance,100% ozone-free
  • No electric filtrations
  • Single filter replacement indicator


Does dust aggravate eczema?

Yes, dust and dust mites often cause allergic reactions, which can trigger eczema outbreaks.

If you find that dust aggravates your eczema, it is a good idea to get an air purifier to remove dust particles from the air.


Although Atopic dermatitis (Eczema) and other such conditions have been known for quite some time now, there isn’t any solid solution to them. Air purifiers bring a viable solution that can help with Eczema flare-ups and can improve the overall quality of life by removing allergens and other irritants from the indoor air.

All the air purifiers we covered offered respectable protection against most allergens and will help you live your life to the fullest.